End to the vicious cycle. Tropical countries have very rich biodiversity due to geographic location on planet earth. Diverse flora and fauna thrive here, so are the tiny microbes and pathogens causing variety of diseases. The disease of countries in tropics are more prevalent and causative agents are different like poverty, Disorders (communicable and non communicable), International highlight and power, priority etc., Due to huge population, tropics are world market hits which has now been in the case of pharmaceuticals too. The ever increasing budget of drug discovery, testing, trials and downstream processing has a need of huge marketing target. The trap in which countries like India has fallen in recent years. The number of new drugs onto market is having a declining trend currently but the cost spent for medicines has increased drastically. Increase in literacy rate and accessible medical facilities has increased country's patient load and costumers for pharmaceutical industries. This vicious cycle must end as it just preys and promises fake relief from disease but causes stress and tension in terms of expenditure (which also is a disease). From the view of Vector borne diseases, drug resistance is an important factor to consider as in a span of years we may not have a stock of curable drugs to treat affected people. Thus an initiative such as open source pharma is indeed necessary to take this revolution in pharmaceutical research and product development to answer sufferings of millions awaiting in vulnerable shed.